variant_key |
str |
required |
|
The subject's variant_key; joins clin_sig_concordance.csv |
genotype |
str |
required |
|
The authored genotype; the second half of the join onto clin_sig_concordance.csv |
authority |
str |
required |
|
Which annotation authority this call is from: clinvar|pubmind|manual (open). An authoritative ANNOTATION source in the sense ClinVar is one — never resolution.csv's authority, which names whoever supplied a coordinate. |
status |
str |
required |
one of: no_record, recorded, unchecked |
What happened when this authority was consulted: recorded|no_record|unchecked. no_record is an established absence — asked, and it has nothing here. unchecked is nobody-asked: no snapshot was provisioned, or one was present and not queryable. The two are never interchangeable, and neither is agreement. |
clin_sig |
str | None |
optional |
one of: affects, association, benign, conflicting, drug_response, likely_benign, likely_pathogenic, not_provided, other, pathogenic, protective, risk_factor, uncertain_significance |
The authority's classification, normalized to this format's own vocabulary by the one shared significance normalizer every snapshot builder calls. Empty on no_record and on unchecked: an unknown is withheld, never written down as a negative. |
clin_sig_raw |
str | None |
optional |
|
The authority's verbatim wording (Conflicting_classifications_of_pathogenicity, Uncertain significance), kept so the normalization above stays auditable and a term this release does not model is still visible. |
confidence |
str | None |
optional |
|
How much the authority stands behind this call, in ITS OWN units and unconverted — ClinVar's gold-star count, a miner's evidence-depth count. A string because the instruments are not the same quantity, so a numeric column would invite an arithmetic nobody can justify. Meaningless without confidence_unit beside it. |
confidence_unit |
str | None |
optional |
|
Which instrument confidence is measured on, e.g. 'review_stars'. Required whenever confidence is set: a magnitude with no unit beside it is a number nothing can read, and this format has paid for that once already on weight. |
dataset |
str | None |
optional |
|
Which release of the authority answered, e.g. 'clinvar_2026-08-01'. A FACT, on the rule every sibling applies: two releases are two facts about the world. |
checked_at |
str | None |
optional |
|
ISO-8601 UTC timestamp of the consultation that wrote this row. Canonicalized on load, and outside the fact set for the reason fetched_at is outside every sibling. |