Mitochondrial DNA and animal longevity

Why do some animals live 507 years and others 1.9 months?

Compare the mitochondrial genomes of 2,335 species, from base composition to codon usage, against their maximum lifespan.

2,335
species with a complete mtDNA
23
classes, 176 orders
13
protein-coding genes per genome
507 yr
longest lifespan: Ocean quahog clam

GC content against lifespan

Whole mtDNA, all 2,335 species
10203040501 yr10 yr100 yrMaximum lifespan, log scaleGC %HumanBowhead whaleNaked mole-ratHouse mouseOcean quahog clam

Hover or tap a point to see the species; select it again to open its page. Legend buttons spotlight a class.

What you can do

2 (2026-11-13) · data from MitoAge build 1, NCBI RefSeq mitochondrion release, NCBI Taxonomy (new_taxdump), AnAge, FishBase, SeaLifeBase, USGS Bird Banding Laboratory longevity records, EURING longevity list, NCBI RefSeq records cited by build 1 (E-utilities efetch, cached), Open Tree of Life synthetic tree, TimeTree 5